|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse|
|Dilution||IHC-P (5 µg/ml), WB (0.5-4 µg/ml),|
|Other Names||Stromelysin-1, SL-1, 188.8.131.52, Matrix metalloproteinase-3, MMP-3, Transin-1, MMP3, STMY1|
|Target/Specificity||The antibody recognizes the MMP-3 of human, mouse, rat, horse, and rabbit origins. Reactivity to other species has not been tested. The antibody detects the 55 kD full length and the 21 kD cleavage fragment of MMP-3.|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||MMP3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
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Provided below are standard protocols that you may find useful for product applications.
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
Saus J.,et al.J. Biol. Chem. 263:6742-6745(1988).
Whitham S.E.,et al.Biochem. J. 240:913-916(1986).
Wilhelm S.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:6725-6729(1987).
Lin D.,et al.Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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