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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MGLL / Monoacylglycerol Lipase Antibody (Internal)   

MGLL / Monoacylglycerol Lipase Antibody (Internal)

Goat Polyclonal Antibody

     
  • WB - MGLL / Monoacylglycerol Lipase Antibody (Internal) ALS13359
    Antibody (0.5 ug/ml) staining of Human Adipose lysate (35 ug protein in RIPA buffer).
  • IHC - MGLL / Monoacylglycerol Lipase Antibody (Internal) ALS13359
    Anti-MGLL antibody IHC of human liver.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q99685
Reactivity Human, Mouse, Rat, Rabbit, Hamster, Monkey
Host Goat
Clonality Polyclonal
Calculated MW 33kDa
Dilution ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.5-1.5 µg/ml)
Additional Information
Gene ID 11343
Other Names Monoglyceride lipase, MGL, 3.1.1.23, HU-K5, Lysophospholipase homolog, Lysophospholipase-like, Monoacylglycerol lipase, MAGL, MGLL
Target/Specificity Human MGLL. This antibody is expected to recognize both reported isoforms (NP_009214.1; NP_001003794.1).
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsMGLL / Monoacylglycerol Lipase Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MGLL (HGNC:17038)
Function Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth (PubMed:20079333).
Cellular Location Cytoplasm, cytosol {ECO:0000250|UniProtKB:O35678}. Membrane {ECO:0000250|UniProtKB:O35678}; Peripheral membrane protein {ECO:0000250|UniProtKB:O35678}
Tissue Location Detected in adipose tissue, lung, liver, kidney, brain and heart.
Research Areas
Citations (0)

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Background

Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.

References

Wall E.M.,et al.Virus Res. 52:157-167(1997).
Karlsson M.,et al.Gene 272:11-18(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Muzny D.M.,et al.Nature 440:1194-1198(2006).

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$ 395.00
Cat# ALS13359
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