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MGLL / Monoacylglycerol Lipase Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q99685 |
| Reactivity | Human, Mouse, Rat, Rabbit, Hamster, Monkey |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 33kDa |
| Dilution | ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.5-1.5 µg/ml) |
| Gene ID | 11343 |
|---|---|
| Other Names | Monoglyceride lipase, MGL, 3.1.1.23, HU-K5, Lysophospholipase homolog, Lysophospholipase-like, Monoacylglycerol lipase, MAGL, MGLL |
| Target/Specificity | Human MGLL. This antibody is expected to recognize both reported isoforms (NP_009214.1; NP_001003794.1). |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | MGLL / Monoacylglycerol Lipase Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MGLL (HGNC:17038) |
|---|---|
| Function | Converts monoacylglycerides to free fatty acids and glycerol (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842). Hydrolyzes the endocannabinoid 2- arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth (PubMed:20079333). |
| Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:O35678}. Membrane {ECO:0000250|UniProtKB:O35678}; Peripheral membrane protein {ECO:0000250|UniProtKB:O35678} |
| Tissue Location | Detected in adipose tissue, lung, liver, kidney, brain and heart. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.
References
Wall E.M.,et al.Virus Res. 52:157-167(1997).
Karlsson M.,et al.Gene 272:11-18(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Muzny D.M.,et al.Nature 440:1194-1198(2006).
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