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MYST3 / MOZ Antibody (Internal)

Goat Polyclonal Antibody

     
  • IHC - MYST3 / MOZ Antibody (Internal) ALS13375
    Anti-MYST3 antibody IHC of human adrenal.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q92794
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 225kDa
Dilution ELISA (1:16000), IHC-P (3.75 µg/ml),
Additional Information
Gene ID 7994
Other Names Histone acetyltransferase KAT6A, 2.3.1.48, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3, MYST-3, Monocytic leukemia zinc finger protein, Runt-related transcription factor-binding protein 2, Zinc finger protein 220, KAT6A, MOZ, MYST3, RUNXBP2, ZNF220
Target/Specificity Human MYST3. Reported variants NP_001092882.1, NP_006757.2, NP_001092883.1 represent identical protein.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsMYST3 / MOZ Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KAT6A
Synonyms MOZ, MYST3, RUNXBP2, ZNF220
Function Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML.
Cellular Location Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus, PML body. Note=Recruited into PML body after DNA damage
Citations (0)

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Background

Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML.

References

Borrow J.,et al.Nat. Genet. 14:33-41(1996).
Nusbaum C.,et al.Nature 439:331-335(2006).
Hosoda F.,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Carapeti M.,et al.Blood 91:3127-3133(1998).
Chaffanet M.,et al.Genes Chromosomes Cancer 28:138-144(2000).

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$ 395.00
Cat# ALS13375
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