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DCYTB / CYBRD1 Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • IHC - DCYTB / CYBRD1 Antibody (C-Terminus) ALS13423
    Anti-CYBRD1 / DCYTB antibody IHC of human small intestine.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q53TN4
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 32kDa
Dilution ELISA (1:16000), IHC-P (2.5 µg/ml),
Additional Information
Gene ID 79901
Other Names Cytochrome b reductase 1, 1.-.-.-, Duodenal cytochrome b, Ferric-chelate reductase 3, CYBRD1, DCYTB, FRRS3
Target/Specificity Human CYBRD1 / DCYTB. This antibody is expected to recognise isoform 1 (NP_079119.3) only.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsDCYTB / CYBRD1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYBRD1
Synonyms DCYTB, FRRS3
Function Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells.
Cellular Location Membrane; Multi-pass membrane protein
Tissue Location Present in erythrocyte membranes (at protein level). Also expressed in respiratory epithelium
Research Areas
Citations (0)

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Background

Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells.

References

Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Zaahl M.G.,et al.Hum. Genet. 115:409-417(2004).

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$ 395.00
Cat# ALS13423
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