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SAR1A / SAR1 Antibody (Internal)

Goat Polyclonal Antibody

     
  • WB - SAR1A / SAR1 Antibody (Internal) ALS13436
    Antibody (0.1 ug/ml) staining of NIH3T3 lysate (35 ug protein in RIPA buffer).
    detail
  • IHC - SAR1A / SAR1 Antibody (Internal) ALS13436
    Anti-SAR1A antibody IHC of human small intestine.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9NR31
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 22kDa
Dilution ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml)
Additional Information
Gene ID 56681
Other Names GTP-binding protein SAR1a, COPII-associated small GTPase, SAR1A, SAR1, SARA, SARA1
Target/Specificity Human SAR1A.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsSAR1A / SAR1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SAR1A
Synonyms SAR1, SARA, SARA1
Function Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).
Cellular Location Endoplasmic reticulum. Golgi apparatus
Research Areas
Citations (0)
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Background

Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).

References

South S.T.,et al.J. Cell Biol. 149:1345-1360(2000).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Pietas A.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 429:375-381(2004).

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Discontinued
Cat# ALS13436
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