SAR1A / SAR1 Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q9NR31 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 22kDa |
Dilution | ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml) |
Gene ID | 56681 |
---|---|
Other Names | GTP-binding protein SAR1a, COPII-associated small GTPase, SAR1A, SAR1, SARA, SARA1 |
Target/Specificity | Human SAR1A. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | SAR1A / SAR1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SAR1A |
---|---|
Synonyms | SAR1, SARA, SARA1 |
Function | Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES). |
Cellular Location | Endoplasmic reticulum. Golgi apparatus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).
References
South S.T.,et al.J. Cell Biol. 149:1345-1360(2000).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Pietas A.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 429:375-381(2004).
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