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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Zyxin Antibody (clone 2D1)   

Zyxin Antibody (clone 2D1)

Mouse Monoclonal Antibody

     
  • WB - Zyxin Antibody (clone 2D1) ALS13440
    ZYX monoclonal antibody, clone 2D1 Western blot of ZYX expression in NIH/3T3.
  • IHC - Zyxin Antibody (clone 2D1) ALS13440
    Anti-ZYX / Zyxin antibody IHC of human breast.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q15942
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Clone Names 2D1
Calculated MW 61kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 7791
Other Names Zyxin, Zyxin-2, ZYX
Reconstitution & Storage Store at -20°C. Aliquot to avoid freeze/thaw cycles.
PrecautionsZyxin Antibody (clone 2D1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZYX
Function Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression (By similarity).
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Cell junction, focal adhesion. Note=Associates with the actin cytoskeleton near the adhesion plaques. Enters the nucleus in the presence of HESX1
Research Areas
Citations (0)

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Background

Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression (By similarity).

References

Macalma T.,et al.J. Biol. Chem. 271:31470-31478(1996).
Zumbrunn J.,et al.Eur. J. Biochem. 241:657-663(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 424:157-164(2003).

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$ 450.00
Cat# ALS13440
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