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WDR20 Antibody (clone 2A6)

Mouse Monoclonal Antibody

     
  • WB - WDR20 Antibody (clone 2A6) ALS13502
    WDR20 monoclonal antibody, clone 2A6 Western blot of WDR20 expression in HeLa NE.
    detail
  • IF - WDR20 Antibody (clone 2A6) ALS13502
    Immunofluorescence of monoclonal antibody to WDR20 on HeLa cell (antibody concentration 10 ug/ml).
    detail
  • IHC - WDR20 Antibody (clone 2A6) ALS13502
    Anti-WDR20 antibody IHC of human brain, cortex.
    detail
  • IHC - WDR20 Antibody (clone 2A6) ALS13502
    Anti-WDR20 antibody IHC of human spleen.
    detail
  • IHC - WDR20 Antibody (clone 2A6) ALS13502
    Anti-WDR20 antibody IHC of human testis.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q8TBZ3
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2A6
Calculated MW 63kDa
Dilution IF (10 µg/ml), IHC-P (5 µg/ml),
Additional Information
Gene ID 91833
Other Names WD repeat-containing protein 20, Protein DMR, WDR20
Reconstitution & Storage Store at -20°C. Aliquot to avoid freeze/thaw cycles.
PrecautionsWDR20 Antibody (clone 2A6) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WDR20
Function Regulator of deubiquitinating complexes. Activates deubiquitinating activity of complexes containing USP12 (PubMed:20147737, PubMed:27373336). Anchors at the base of the ubiquitin-contacting loop of USP12 and remotely modulates the catalytic center of the enzyme (PubMed:27373336). Regulates shuttling of the USP12 deubiquitinase complex between the plasma membrane, cytoplasm and nucleus (PubMed:30466959).
Cellular Location Cytoplasm. Nucleus
Citations (0)
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References

Li W.B.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Heilig R.,et al.Nature 421:601-607(2003).
Li N.,et al.Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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Discontinued
Cat# ALS13502
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