|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||Zinc finger BED domain-containing protein 3, Axin-interacting protein, ZBED3|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||ZBED3 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin. Involved in transcription activation of Wnt target gene expression (By similarity).|
|Cellular Location||Cytoplasm. Membrane. Note=Colocalizes with AXIN1 in the cytoplasm|
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Provided below are standard protocols that you may find useful for product applications.
Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin. Involved in transcription activation of Wnt target gene expression (By similarity).
Schmutz J.,et al.Nature 431:268-274(2004).
Daub H.,et al.Mol. Cell 31:438-448(2008).
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