|Application ||WB, IHC-P, IF, E|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||FERM and PDZ domain-containing protein 4, PDZ domain-containing protein 10, PSD-95-interacting regulator of spine morphogenesis, Preso, FRMPD4, KIAA0316, PDZD10, PDZK10|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||FRMPD4 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA0316, PDZD10, PDZK10|
|Function||Positive regulator of dendritic spine morphogenesis and density. Required for the maintenance of excitatory synaptic transmission. Binds phosphatidylinositol 4,5-bisphosphate.|
|Cellular Location||Cell projection, dendritic spine|
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Provided below are standard protocols that you may find useful for product applications.
Positive regulator of dendritic spine morphogenesis and density. Required for the maintenance of excitatory synaptic transmission. Binds phosphatidylinositol 4,5-bisphosphate.
Nagase T.,et al.DNA Res. 4:141-150(1997).
Ohara O.,et al.Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Lee H.W.,et al.J. Neurosci. 28:14546-14556(2008).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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