GAREM / FAM59A Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | Q9H706 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 97kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 64762 |
---|---|
Other Names | GRB2-associated and regulator of MAPK protein, GRB2-associated and regulator of MAPK1, GAREM, C18orf11, FAM59A |
Target/Specificity | Human FAM59A |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | GAREM / FAM59A Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GAREM1 |
---|---|
Synonyms | C18orf11, FAM59A, GAREM |
Function | [Isoform 1]: Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation. |
Tissue Location | Isoform 1 is ubiquitously expressed. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Isoform 1: Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Tashiro K.,et al.J. Biol. Chem. 284:20206-20214(2009).
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