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EFHD2 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - EFHD2 Antibody (N-Terminus) ALS13561
    Immunofluorescence of EFHD2 in human brain tissue with EFHD2 antibody at 20 ug/ml.
  • IHC - EFHD2 Antibody (N-Terminus) ALS13561
    Anti-EFHD2 antibody IHC of human thymus.
  • IHC - EFHD2 Antibody (N-Terminus) ALS13561
    Anti-EFHD2 antibody IHC of human tonsil.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q96C19
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 27kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 79180
Other Names EF-hand domain-containing protein D2, Swiprosin-1, EFHD2, SWS1
Target/Specificity Human EFHD2
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsEFHD2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EFHD2
Synonyms SWS1
Function May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
Cellular Location Membrane raft. Note=In a mouse immature B-cell line WEHI-231.
Tissue Location Found in lymphocytes; preferentially expressed in CD8+ cells.
Research Areas
Citations (0)

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Background

May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.

References

Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (FEB-2008) to UniProtKB.
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Vuadens F.,et al.Proteomics 2:105-111(2002).

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$ 395.00
Cat# ALS13561
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