|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml), WB (1:500-1:3000),|
|Other Names||Platelet glycoprotein Ib beta chain, GP-Ib beta, GPIb-beta, GPIbB, Antigen CD42b-beta, CD42c, GP1BB|
|Reconstitution & Storage||Aliquot and store at -20°C. Minimize freezing and thawing.|
|Precautions||GP1BB / CD42c Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in heart and brain.|
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Provided below are standard protocols that you may find useful for product applications.
Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium.
Lopez J.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:2135-2139(1988).
Yagi M.,et al.J. Biol. Chem. 269:17424-17427(1994).
Kelly M.D.,et al.J. Clin. Invest. 93:2417-2424(1994).
Zieger B.,et al.J. Clin. Invest. 99:520-525(1997).
Kunishima S.,et al.Blood 89:2404-2412(1997).
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