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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   FOXN1 Antibody   

FOXN1 Antibody

Rabbit Polyclonal Antibody

  • WB - FOXN1 Antibody ALS13641
    Sample (30 ug of whole cell lysate). A: Raji. 7.5% SDS PAGE. FOXN1 antibody diluted at 1:1000.
  • IHC - FOXN1 Antibody ALS13641
    Anti-FOXN1 antibody IHC of human uterus.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15353
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 69kDa
Dilution IHC-P (10 µg/ml), WB (1:500-1:3000),
Additional Information
Gene ID 8456
Other Names Forkhead box protein N1, Winged-helix transcription factor nude, FOXN1, RONU, WHN
Target/Specificity Human Forkhead box N1.
Reconstitution & Storage Aliquot and store at -20°C. Minimize freezing and thawing.
PrecautionsFOXN1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXN1
Synonyms RONU, WHN
Function Transcriptional regulator which regulates the development, differentiation, and function of thymic epithelial cells (TECs) both in the prenatal and postnatal thymus. Acts as a master regulator of the TECs lineage development and is required from the onset of differentiation in progenitor TECs in the developing fetus to the final differentiation steps through which TECs mature to acquire their full functionality. Regulates, either directly or indirectly the expression of a variety of genes that mediate diverse aspects of thymus development and function, including MHC Class II, DLL4, CCL25, CTSL, CD40 and PAX1. Regulates the differentiation of the immature TECs into functional cortical TECs (cTECs) and medullary TECs (mTECs). Essential for maintenance of mTECs population in the postnatal thymus. Involved in the morphogenesis and maintenance of the three-dimensional thymic microstructure which is necessary for a fully functional thymus. Plays an important role in the maintenance of hematopoiesis and particularly T lineage progenitors within the bone marrow niche with age. Essential for the vascularization of the thymus anlage. Promotes the terminal differentiation of epithelial cells in the epidermis and hair follicles, partly by negatively regulating the activity of protein kinase C (By similarity). Plays a crucial role in the early prenatal stages of T cell ontogeny (PubMed:21507891).
Cellular Location Nucleus.
Tissue Location Expressed in thymus.
Volume 50 µl
Research Areas
Citations (0)

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Transcriptional regulator involved in development.


Schorpp M.,et al.Immunogenetics 46:509-515(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Frank J.,et al.Nature 398:473-474(1999).

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$ 395.00
Cat# ALS13641
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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