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RAD51AP1 Antibody

Rabbit Polyclonal Antibody

     
  • WB - RAD51AP1 Antibody ALS13647
    Sample(30 g of whole cell lysate). A: Raji. 12% SDS PAGE. RAD51AP1 antibody diluted at 1:500.
  • IHC - RAD51AP1 Antibody ALS13647
    Anti-RAD51AP1 antibody IHC of human small intestine, submucosal plexus.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q96B01
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 38kDa
Dilution IHC-P (10 µg/ml), WB (1:500-1:3000),
Additional Information
Gene ID 10635
Other Names RAD51-associated protein 1, RAD51-interacting protein, R51A1
Target/Specificity Human RAD51AP1.
Reconstitution & Storage Aliquot and store at -20°C. Minimize freezing and thawing.
PrecautionsRAD51AP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name R51A1
Function May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.
Cellular Location Nucleus. Note=Colocalizes with RAD51 to multiple nuclear foci.
Tissue Location Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes
Volume 50 µl
Citations (0)

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Background

May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.

References

Kovalenko O.V.,et al.Nucleic Acids Res. 25:4946-4953(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Kovalenko O.V.,et al.Nucleic Acids Res. 34:5081-5092(2006).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).

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$ 395.00
Cat# ALS13647
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