|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:20000), IHC-P (10 µg/ml), WB (1:500-1:1000)|
|Other Names||Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein, ACTN3|
|Target/Specificity||ACTN3 Antibody detects endogenous levels of total ACTN3 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||ACTN3 Antibody (aa1-50) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.|
|Tissue Location||Expressed only in a subset of type 2 skeletal muscle fibers.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Beggs A.H.,et al.J. Biol. Chem. 267:9281-9288(1992).
Taylor T.D.,et al.Nature 440:497-500(2006).
Mills M.,et al.Hum. Mol. Genet. 10:1335-1346(2001).
Takada F.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:1595-1600(2001).
Bienvenut W.V.,et al.Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
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