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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   AS3MT Antibody (N-Terminus)   

AS3MT Antibody (N-Terminus)

Goat Polyclonal Antibody

     
  • IHC - AS3MT Antibody (N-Terminus) ALS13693
    Anti-AS3MT antibody IHC of human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q9HBK9
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 42kDa
Dilution ELISA (1:32000), IHC-P (3.75 µg/ml),
Additional Information
Gene ID 57412
Other Names Arsenite methyltransferase, 2.1.1.137, Methylarsonite methyltransferase, S-adenosyl-L-methionine:arsenic(III) methyltransferase, AS3MT, CYT19
Target/Specificity Human AS3MT.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsAS3MT Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AS3MT
Synonyms CYT19
Function Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me- AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH (By similarity).
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Background

Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me- AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH (By similarity).

References

Wood T.C.,et al.J. Biol. Chem. 281:7364-7373(2006).
Xiao H.,et al.Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
Yu L.,et al.Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS13693
Size:
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(40 western blots)
Availability: 5 days
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