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PGLYRP1 / PGRP Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • WB - PGLYRP1 / PGRP Antibody (C-Terminus) ALS13704
    Antibody (0.3 ug/ml) staining of Jurkat lysate (35 ug protein in RIPA buffer).
  • IHC - PGLYRP1 / PGRP Antibody (C-Terminus) ALS13704
    Anti-PGLYRP1 / PGRP antibody IHC of human spleen.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O75594
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 22kDa
Dilution ELISA (1:4000), IHC-P (3.75 µg/ml), WB (0.3-1 µg/ml)
Additional Information
Gene ID 8993
Other Names Peptidoglycan recognition protein 1, Peptidoglycan recognition protein short, PGRP-S, PGLYRP1, PGLYRP, PGRP, TNFSF3L
Target/Specificity Human PGLYRP1 / PGRP.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsPGLYRP1 / PGRP Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PGLYRP1
Synonyms PGLYRP, PGRP, TNFSF3L
Function Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity.
Cellular Location Secreted. Cytoplasmic granule
Tissue Location Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils
Research Areas
Citations (0)

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Background

Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity.

References

Kang D.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:10078-10082(1998).
Wan T.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Grimwood J.,et al.Nature 428:529-535(2004).
Liu C.,et al.J. Biol. Chem. 276:34686-34694(2001).

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$ 395.00
Cat# ALS13704
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