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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SCARA5 Antibody (C-Terminus)   

SCARA5 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • ICC - SCARA5 Antibody (C-Terminus) ALS13756
    Immunocytochemistry of SCARA5 in HepG2 cells with SCARA5 antibody at 2.5 ug/ml.
  • IF - SCARA5 Antibody (C-Terminus) ALS13756
    Immunofluorescence of SCARA5 in HepG2 cells with SCARA5 antibody at 20 ug/ml.
  • WB - SCARA5 Antibody (C-Terminus) ALS13756
    Western blot of SCARA5 in human liver tissue lysate with SCARA5 antibody at 1 ug/ml.
  • IHC - SCARA5 Antibody (C-Terminus) ALS13756
    Anti-SCARA5 antibody IHC of human small intestine.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, ICC, E
Primary Accession Q6ZMJ2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 54kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 286133
Other Names Scavenger receptor class A member 5, Scavenger receptor hlg, SCARA5
Target/Specificity Human SCARA5
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsSCARA5 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SCARA5 {ECO:0000255|HAMAP-Rule:MF_03070}
Function Ferritin receptor that mediates non-transferrin- dependent delivery of iron. Mediates cellular uptake of ferritin- bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type- specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).
Cellular Location Cell membrane {ECO:0000255|HAMAP- Rule:MF_03070}; Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_03070}
Research Areas
Citations (0)

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Background

Ferritin receptor that mediates non-transferrin- dependent delivery of iron. Mediates cellular uptake of ferritin- bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type- specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1) (By similarity).

References

Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Lin L.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS13756
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