SYNGR2 / Synaptogyrin 2 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
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Primary Accession | O43760 |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 25kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 9144 |
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Other Names | Synaptogyrin-2, Cellugyrin, SYNGR2 |
Target/Specificity | Human SYNGR2 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | SYNGR2 / Synaptogyrin 2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SYNGR2 (HGNC:11499) |
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Function | May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane. |
Cellular Location | Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:O54980}; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:O54980}; Multi-pass membrane protein. Note=Localizes to cytoplasmic vesicles associated with the recycling endosomes. {ECO:0000250|UniProtKB:O54980} |
Tissue Location | Ubiquitous; low expression in brain. |
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Provided below are standard protocols that you may find useful for product applications.
References
Kedra D.,et al.Hum. Genet. 103:131-141(1998).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Bienvenut W.V.,et al.Submitted (FEB-2005) to UniProtKB.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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