LRRC19 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, ICC, E |
---|---|
Primary Accession | Q9H756 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 42kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 64922 |
---|---|
Other Names | Leucine-rich repeat-containing protein 19, LRRC19 |
Target/Specificity | Human LRRC19 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | LRRC19 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LRRC19 (HGNC:23379) |
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Function | Pathogen-recognition receptor which mediates the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of pro-inflammatory cytokines (PubMed:19679103, PubMed:25026888). In kidney, prevents infection by uropathogenic bacteria by inducing the production of cytokines, chemokines and antimicrobial substances. In gut, involved in host-microbiota interactions, plays a critical role in promoting the recruitment of immune cells and intestinal inflammation (By similarity). |
Cellular Location | Membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in renal collecting duct epithelial cells. |
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Provided below are standard protocols that you may find useful for product applications.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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