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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   CFTR Antibody (aa2-14)   

CFTR Antibody (aa2-14)

Goat Polyclonal Antibody

     
  • IHC - CFTR Antibody (aa2-14) ALS13843
    Anti-CFTR antibody IHC of human kidney.
  • IHC - CFTR Antibody (aa2-14) ALS13843
    Anti-CFTR antibody IHC of human prostate.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P13569
Reactivity Human, Monkey, Sheep, Bovine
Host Goat
Clonality Polyclonal
Calculated MW 168kDa
Dilution IHC-P (2.5-5 µg/ml)
Additional Information
Gene ID 1080
Other Names Cystic fibrosis transmembrane conductance regulator, CFTR, ATP-binding cassette sub-family C member 7, Channel conductance-controlling ATPase, 3.6.3.49, cAMP-dependent chloride channel, CFTR, ABCC7
Target/Specificity Human CFTR.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsCFTR Antibody (aa2-14) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CFTR
Synonyms ABCC7
Function Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
Cellular Location Early endosome membrane; Multi-pass membrane protein. Cell membrane; Multi- pass membrane protein. Note=In the oviduct and bronchus, detected on the apical side of epithelial cells, but not associated with cilia.
Tissue Location Expressed in the respiratory airway, including bronchial epithelium, and in the female reproductive tract, including oviduct (at protein level)
Research Areas
Citations (0)

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Background

Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.

References

Riordan J.R.,et al.Science 245:1066-1073(1989).
Zielenski J.,et al.Genomics 10:214-228(1991).
Stacy R.,et al.Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 424:157-164(2003).
Scherer S.W.,et al.Science 300:767-772(2003).

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$ 395.00
Cat# ALS13843
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