|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (2.5 µg/ml), WB (1-2 µg/ml),|
|Other Names||Calcium-binding protein 8, CaBP8, Calneuron I, Calneuron-1, CALN1, CABP8|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||Calneuron-1 / CALN1 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity). May play a role in the physiology of neurons and is potentially important in memory and learning.|
|Cellular Location||Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Cytoplasm, perinuclear region. Cell membrane; Single-pass type IV membrane protein|
|Tissue Location||Brain specific.|
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Provided below are standard protocols that you may find useful for product applications.
Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity). May play a role in the physiology of neurons and is potentially important in memory and learning.
Wu Y.-Q.,et al.Mol. Genet. Metab. 72:343-350(2001).
Haeseleer F.,et al.Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 424:157-164(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
McCue H.V.,et al.Biochem. Biophys. Res. Commun. 380:825-831(2009).
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