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SLC39A3 / ZIP3 Antibody (Internal)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9BRY0 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 34kDa |
| Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
| Gene ID | 29985 |
|---|---|
| Other Names | Zinc transporter ZIP3, Solute carrier family 39 member 3, Zrt- and Irt-like protein 3, ZIP-3, SLC39A3, ZIP3 |
| Target/Specificity | Human SLC39A3 |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Precautions | SLC39A3 / ZIP3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC39A3 (HGNC:17128) |
|---|---|
| Synonyms | ZIP3 |
| Function | Transporter for the divalent cation Zn(2+). Mediates the influx of Zn(2+) into cells from extracellular space. Controls Zn(2+) accumulation into dentate gyrus granule cells in the hippocampus. Mediates Zn(2+) reuptake from the secreted milk within the alveolar lumen. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q99K24}; Multi-pass membrane protein. Apical cell membrane {ECO:0000250|UniProtKB:Q99K24}; Multi-pass membrane protein. Note=Localized primarily at the cell surface but also found in a perinuclear compartment in HC11 cells. In mammary epithelial cell, localized primary to the apical membrane {ECO:0000250|UniProtKB:Q99K24} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Acts as a zinc-influx transporter.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Daub H.,et al.Mol. Cell 31:438-448(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
Olsen J.V.,et al.Sci. Signal. 3:RA3-RA3(2010).
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