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>   home   >   Products   >   Primary Antibodies   >   DHX9 Antibody (clone 3G7)   

DHX9 Antibody (clone 3G7)

Mouse Monoclonal Antibody

     
  • WB - DHX9 Antibody (clone 3G7) ALS14038
    DHX9 monoclonal antibody, clone 3G7 Western blot of DHX9 expression in HeLa nuclear extract.
  • IF - DHX9 Antibody (clone 3G7) ALS14038
    Immunofluorescence of monoclonal antibody to DHX9 on HeLa cell. [antibody concentration 10 ug/ml]
  • IHC - DHX9 Antibody (clone 3G7) ALS14038
    Anti-DHX9 antibody IHC of human kidney, tubules.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q08211
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3G7
Calculated MW 141kDa
Dilution IF (10 µg/ml), IHC-P (5 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 1660
Other Names ATP-dependent RNA helicase A, RHA, 3.6.4.13, DEAH box protein 9, Leukophysin, LKP, Nuclear DNA helicase II, NDH II, DHX9, DDX9, LKP, NDH2
Target/Specificity Human DHX9
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsDHX9 Antibody (clone 3G7) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DHX9
Synonyms DDX9, LKP, NDH2
Function Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alteration of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Component of the CRD- mediated complex that promotes MYC mRNA stability. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms. Positively regulates HIV-1 LTR-directed gene expression.
Cellular Location Nucleus, nucleolus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Can shuttle between nucleus and cytoplasm
Citations (0)

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Background

Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alteration of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Component of the CRD- mediated complex that promotes MYC mRNA stability. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms. Positively regulates HIV-1 LTR-directed gene expression.

References

Lee C.-G.,et al.J. Biol. Chem. 268:16822-16830(1993).
Abdelhaleem M.M.,et al.J. Immunol. 156:2026-2035(1996).
Zhang S.,et al.J. Biol. Chem. 272:11487-11494(1997).
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).
Gregory S.G.,et al.Nature 441:315-321(2006).

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$ 450.00
Cat# ALS14038
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