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MKNK1 / MNK1 Antibody (clone 2F12)

Mouse Monoclonal Antibody

     
  • WB - MKNK1 / MNK1 Antibody (clone 2F12) ALS14073
    MNK1 monoclonal antibody, clone 2F12.
  • IF - MKNK1 / MNK1 Antibody (clone 2F12) ALS14073
    Immunofluorescence of monoclonal antibody to MNK1 on HeLa cell. [antibody concentration 10 ug/ml]
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q9BUB5
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2F12
Calculated MW 51kDa
Dilution IF (10 µg/ml), IHC-P (5 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 8569
Other Names MAP kinase-interacting serine/threonine-protein kinase 1, 2.7.11.1, MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, Mnk1, MKNK1, MNK1
Target/Specificity Human MNK1
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsMKNK1 / MNK1 Antibody (clone 2F12) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MKNK1
Synonyms MNK1
Function May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap.
Cellular Location Isoform 2: Cytoplasm.
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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Background

May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap.

References

Fukunaga R.,et al.EMBO J. 16:1921-1933(1997).
Knauf U.,et al.Mol. Cell. Biol. 21:5500-5511(2001).
O'Loghlen A.,et al.Exp. Cell Res. 299:343-355(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 450.00
Cat# ALS14073
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