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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TIMP2 Antibody (clone 5B11)   

TIMP2 Antibody (clone 5B11)

Mouse Monoclonal Antibody

     
  • IF - TIMP2 Antibody (clone 5B11) ALS14164
    Immunofluorescence of monoclonal antibody to TIMP2 on HeLa cell. [antibody concentration 10 ug/ml]
  • IHC - TIMP2 Antibody (clone 5B11) ALS14164
    Anti-TIMP2 antibody IHC of human prostate.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P16035
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 5B11
Calculated MW 24kDa
Dilution IF (10 µg/ml), IHC-P (5 µg/ml),
Additional Information
Gene ID 7077
Other Names Metalloproteinase inhibitor 2, CSC-21K, Tissue inhibitor of metalloproteinases 2, TIMP-2, TIMP2
Target/Specificity Human TIMP2
Reconstitution & Storage Store at -20°C, avoid freeze thaw cycles.
PrecautionsTIMP2 Antibody (clone 5B11) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TIMP2
Function Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.

References

Stetler-Stevenson W.G.,et al.J. Biol. Chem. 265:13933-13938(1990).
Boone T.C.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:2800-2804(1990).
Hammani K.,et al.J. Biol. Chem. 271:25498-25505(1996).
Malik K.,et al.Submitted (AUG-1990) to the EMBL/GenBank/DDBJ databases.
Stetler-Stevenson W.G.,et al.J. Biol. Chem. 264:17374-17378(1989).

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$ 450.00
Cat# ALS14164
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