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SEC61A1 / SEC61 Antibody (aa463-476)

Goat Polyclonal Antibody

     
  • WB - SEC61A1 / SEC61 Antibody (aa463-476) ALS14247
    Staining (1 ug/ml) of human cerebellum lysate (35 ug protein in RIPA buffer).
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P61619
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Hamster, Monkey, Pig, Chicken, Horse, Xenopus, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 52kDa
Dilution ELISA (1:8000), IHC-P (3.75 µg/ml), WB (1-3 µg/ml)
Additional Information
Gene ID 29927
Other Names Protein transport protein Sec61 subunit alpha isoform 1, Sec61 alpha-1, SEC61A1, SEC61A
Target/Specificity Human SEC61A1 / SEC61.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsSEC61A1 / SEC61 Antibody (aa463-476) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEC61A1
Synonyms SEC61A
Function Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane- bound ribosomes, either directly or through adapter proteins. Plays a role in pronephric kidney tubule development (By similarity).
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes exclusively in granular structures in the endoplasmic reticulum (ER).
Research Areas
Citations (0)

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Background

Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane- bound ribosomes, either directly or through adapter proteins.

References

Liu T.,et al.Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
Li W.,et al.Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
Finke K.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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$ 395.00
Cat# ALS14247
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