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FDXR Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IP |
|---|---|
| Primary Accession | P22570 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 54kDa |
| Dilution | IHC-P (1:200), WB (1:3000), |
| Gene ID | 2232 |
|---|---|
| Other Names | NADPH:adrenodoxin oxidoreductase, mitochondrial, AR, Adrenodoxin reductase, 1.18.1.6, Ferredoxin--NADP(+) reductase, Ferredoxin reductase, FDXR, ADXR |
| Reconstitution & Storage | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. |
| Precautions | FDXR Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FDXR (HGNC:3642) |
|---|---|
| Synonyms | ADXR |
| Function | Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C- 27 hydroxylation in the liver. |
| Cellular Location | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P48360}; Peripheral membrane protein |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
References
Solish S.B.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:7104-7108(1988).
Lin D.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:8516-8520(1990).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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