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CAPZB / CAPZ Beta Antibody (clone 1H1)

Mouse Monoclonal Antibody

     
  • WB - CAPZB / CAPZ Beta Antibody (clone 1H1) ALS14268
    CAPZB monoclonal antibody, clone 1H1. Western blot of CAPZB expression in HeLa.
  • IHC - CAPZB / CAPZ Beta Antibody (clone 1H1) ALS14268
    Anti-CAPZB antibody IHC of human spleen.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P47756
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1H1
Calculated MW 31kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 832
Other Names F-actin-capping protein subunit beta, CapZ beta, CAPZB
Target/Specificity Human CAPZB
Reconstitution & Storage For long term, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCAPZB / CAPZ Beta Antibody (clone 1H1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CAPZB
Function F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization.
Cellular Location Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere
Research Areas
Citations (0)

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Background

F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization.

References

Barron-Casella E.A.,et al.J. Biol. Chem. 270:21472-21479(1995).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).

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$ 450.00
Cat# ALS14268
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