HURP / DLGAP5 Antibody (aa791-840)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q15398 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 95kDa |
Dilution | ELISA (1:40000), IHC-P (5 µg/ml), WB (1:500-1:1000) |
Gene ID | 9787 |
---|---|
Other Names | Disks large-associated protein 5, DAP-5, Discs large homolog 7, Disks large-associated protein DLG7, Hepatoma up-regulated protein, HURP, DLGAP5, DLG7, KIAA0008 |
Target/Specificity | DLGAP5 Antibody detects endogenous levels of total DLGAP5 protein. |
Reconstitution & Storage | Store at -20°C. |
Precautions | HURP / DLGAP5 Antibody (aa791-840) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DLGAP5 |
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Synonyms | DLG7, KIAA0008 |
Function | Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells. |
Cellular Location | Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells |
Tissue Location | Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta |
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Provided below are standard protocols that you may find useful for product applications.
Background
Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
References
Tsou A.-P.,et al.Oncogene 22:298-307(2003).
Nomura N.,et al.DNA Res. 1:27-35(1994).
Ohara O.,et al.Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
Li W.B.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
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