CST1 / Cystatin SN Antibody (aa31-80)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IF, E |
---|---|
Primary Accession | P01037 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 16kDa |
Dilution | ELISA (1:20000), IF (1:100-1:500), IHC-P (5 µg/ml) |
Gene ID | 1469 |
---|---|
Other Names | Cystatin-SN, Cystain-SA-I, Cystatin-1, Salivary cystatin-SA-1, CST1 |
Target/Specificity | CST1 Antibody detects endogenous levels of total CST1 protein. |
Reconstitution & Storage | Store at -20°C for up to one year. |
Precautions | CST1 / Cystatin SN Antibody (aa31-80) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CST1 |
---|---|
Function | Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well. |
Cellular Location | Secreted. |
Tissue Location | Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in saliva, tears, urine and seminal fluid. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well.
References
Saitoh E.,et al.Gene 61:329-338(1987).
Al-Hashimi I.,et al.J. Biol. Chem. 263:9381-9387(1988).
Deloukas P.,et al.Nature 414:865-871(2001).
Saitoh E.,et al.Biol. Chem. Hoppe-Seyler 369:191-197(1988).
Isemura S.,et al.J. Biochem. 110:648-654(1991).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.