LIG1 / DNA Ligase 1 Antibody (clone 10G12)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P18858 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 10G12 |
Calculated MW | 102kDa |
Dilution | IHC-P (5 µg/ml), WB (1:500-1:1000), |
Gene ID | 3978 |
---|---|
Other Names | DNA ligase 1, 6.5.1.1, DNA ligase I, Polydeoxyribonucleotide synthase [ATP] 1, LIG1 |
Target/Specificity | Human LIG1 |
Reconstitution & Storage | Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
Precautions | LIG1 / DNA Ligase 1 Antibody (clone 10G12) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LIG1 |
---|---|
Function | DNA ligase that seals nicks in double-stranded during DNA repair (PubMed:30395541). Also involved in DNA replication and DNA recombination. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
References
Barnes D.E.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:6679-6683(1990).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Petrini J.H.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:7615-7619(1991).
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