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Neuroserpin Antibody (clone 1D10)

Mouse Monoclonal Antibody

     
  • WB - Neuroserpin Antibody (clone 1D10) ALS14400
    SERPINI1 monoclonal antibody ALS14400, Western blot of SERPINI1 expression in HeLa.
  • IHC - Neuroserpin Antibody (clone 1D10) ALS14400
    Anti-SERPINI1 / Neuroserpin antibody IHC of human brain, cortex.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q99574
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1D10
Calculated MW 46kDa
Dilution IHC-P (5 µg/ml), WB (1:500-1:1000),
Additional Information
Gene ID 5274
Other Names Neuroserpin, Peptidase inhibitor 12, PI-12, Serpin I1, SERPINI1, PI12
Target/Specificity Human Neuroserpin
Reconstitution & Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsNeuroserpin Antibody (clone 1D10) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SERPINI1
Synonyms PI12
Function Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
Cellular Location Secreted.
Tissue Location Predominantly expressed in the brain.
Research Areas
Citations (0)

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Background

Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.

References

Schrimpf S.P.,et al.Genomics 40:55-62(1997).
Kinter J.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 450.00
Cat# ALS14400
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