|Application ||WB, IHC-P, E|
|Dilution||IHC-P (5 µg/ml), WB (1:500-1:1000),|
|Other Names||Neuroserpin, Peptidase inhibitor 12, PI-12, Serpin I1, SERPINI1, PI12|
|Reconstitution & Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||Neuroserpin Antibody (clone 1D10) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.|
|Tissue Location||Predominantly expressed in the brain.|
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Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
Schrimpf S.P.,et al.Genomics 40:55-62(1997).
Kinter J.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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