|Application ||WB, IHC-P, E|
|Dilution||IHC-P (5 µg/ml)|
|Other Names||General vesicular transport factor p115, Protein USO1 homolog, Transcytosis-associated protein, TAP, Vesicle-docking protein, USO1, VDP|
|Reconstitution & Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||US01 / p115 Antibody (clone 3F4) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity.|
|Cellular Location||Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein Note=Recycles between the cytosol and the Golgi apparatus during interphase. During interphase, the phosphorylated form is found exclusively in cytosol; the unphosphorylated form is associated with Golgi apparatus membranes.|
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Provided below are standard protocols that you may find useful for product applications.
General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity).
Sohda M.,et al.J. Biol. Chem. 273:5385-5388(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Hillier L.W.,et al.Nature 434:724-731(2005).
Olsen J.V.,et al.Cell 127:635-648(2006).
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