|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:20000), IHC-P (5 µg/ml), WB (1:500-1:1000)|
|Other Names||Complement C1r subcomponent, 220.127.116.11, Complement component 1 subcomponent r, Complement C1r subcomponent heavy chain, Complement C1r subcomponent light chain, C1R|
|Target/Specificity||C1R (light chain,Cleaved-Ile464) Antibody detects endogenous levels of fragment of activated C1R resulting from cleavage adjacent to Ile464.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||Complement C1R Antibody (aa445-494) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.|
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Provided below are standard protocols that you may find useful for product applications.
C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
Leytus S.P.,et al.Biochemistry 25:4855-4863(1986).
Journet A.,et al.Biochem. J. 240:783-787(1986).
Nakagawa M.,et al.Ann. Hum. Genet. 67:207-215(2003).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Scherer S.E.,et al.Nature 440:346-351(2006).
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