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PYGM Antibody (clone 2C4)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P11217 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2C4 |
| Calculated MW | 97kDa |
| Dilution | IHC-P (5 µg/ml) |
| Gene ID | 5837 |
|---|---|
| Other Names | Glycogen phosphorylase, muscle form, 2.4.1.1, Myophosphorylase, PYGM |
| Target/Specificity | Human PYGM |
| Reconstitution & Storage | For long term, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | PYGM Antibody (clone 2C4) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PYGM (HGNC:9726) |
|---|---|
| Function | Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
References
Burke J.,et al.Proteins 2:177-187(1987).
Kubisch C.,et al.Hum. Mutat. 12:27-32(1998).
Carty M.D.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Taylor T.D.,et al.Nature 440:497-500(2006).
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