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>   home   >   Products   >   Primary Antibodies   >   Cancer   >   PRUNE Antibody (clone 1C11)   

PRUNE Antibody (clone 1C11)

Mouse Monoclonal Antibody

  • WB - PRUNE Antibody (clone 1C11) ALS14521
    Western blot of PRUNE expression in transfected 293T cell line by PRUNE monoclonal antibody,...
  • IHC - PRUNE Antibody (clone 1C11) ALS14521
    Anti-PRUNE antibody IHC of human small intestine.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86TP1
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1C11
Calculated MW 50kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 58497
Other Names Protein prune homolog, hPrune,, Drosophila-related expressed sequence 17, DRES-17, DRES17, HTcD37, PRUNE
Target/Specificity Human PRUNE
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsPRUNE Antibody (clone 1C11) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.
Cellular Location Cytoplasm. Nucleus. Cell junction, focal adhesion. Note=In some transfected cells a nuclear staining is also observed
Tissue Location Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas
Research Areas
Citations (0)

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Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.


Reymond A.,et al.Oncogene 18:7244-7252(1999).
Zollo M.,et al.Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 450.00
Cat# ALS14521
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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