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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CNN2 Antibody   

CNN2 Antibody

Goat Polyclonal Antibody

     
  • WB - CNN2 Antibody ALS14587
    CNN2 antibody (0.03 ug/ml) staining of HepG2 lysates (35 ug protein/ml in RIPA buffer) with (B)...
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q99439
Reactivity Human, Monkey
Host Goat
Clonality Polyclonal
Calculated MW 34kDa
Dilution ELISA (1:32000), IHC-P (2.5-3.75 µg/ml), WB (0.03-0.1 µg/ml)
Additional Information
Gene ID 1265
Other Names Calponin-2, Calponin H2, smooth muscle, Neutral calponin, CNN2
Target/Specificity Human CNN2. This antibody is expected to recognize both reported isoforms (NP_004359.1; NP_958434.1), but it is not expected to cross-react with CCN3.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsCNN2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNN2
Function Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Tissue Location Heart and smooth muscle.
Research Areas
Citations (0)

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Background

Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

References

Masuda H.,et al.J. Biochem. 120:415-424(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Kuromitsu J.,et al.Mol. Cell. Biol. 17:707-712(1997).

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$ 395.00
Cat# ALS14587
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