|Application ||WB, IHC-P, IF|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||Protein-glutamine gamma-glutamyltransferase 5, 22.214.171.124, Transglutaminase X, TG(X), TGX, TGase X, Transglutaminase-5, TGase-5, TGM5, TGMX|
|Target/Specificity||Human TGM5 / Transglutaminase 5. TGM5 antibody is predicted to not cross-react with other TGase protein family members. Multiple isoforms of TGM5 are known to exist.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||TGM5 / Transglutaminase 5 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.|
|Cellular Location||Cytoplasm. Note=Associated with intermediate filaments|
|Tissue Location||Expressed in foreskin keratinocytes.|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.
Aeschlimann D.,et al.J. Biol. Chem. 273:3452-3460(1998).
Grenard P.,et al.J. Biol. Chem. 276:33066-33078(2001).
Rufini A.,et al.Amino Acids 26:425-430(2004).
Cassidy A.J.,et al.Am. J. Hum. Genet. 77:909-917(2005).
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