|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Monkey|
|Dilution||IHC-P (10 µg/ml), WB (1-2 µg/ml),|
|Other Names||Syndecan-4, SYND4, Amphiglycan, Ryudocan core protein, SDC4|
|Target/Specificity||Human SDC4 / Syndecan 4|
|Reconstitution & Storage||Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.|
|Precautions||SDC4 / Syndecan 4 Antibody (aa1-50) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).|
|Cellular Location||Isoform 1: Membrane; Single- pass type I membrane protein. Secreted. Note=Shedding of the ectodomain produces a soluble form.|
|Tissue Location||Expressed in epithelial and fibroblastic cells.|
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Provided below are standard protocols that you may find useful for product applications.
Cell surface proteoglycan that bears heparan sulfate.
David G.,et al.J. Cell Biol. 118:961-969(1992).
Kojima T.,et al.Biochem. Biophys. Res. Commun. 190:814-822(1993).
Takagi A.,et al.J. Biochem. 119:979-984(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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