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CCNO / UNG2 Antibody

Rabbit Polyclonal Antibody

     
  • IHC - CCNO / UNG2 Antibody ALS14920
    Anti-CCNO / Cyclin O antibody IHC of human breast.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P22674
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 38kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 10309
Other Names Cyclin-O, CCNO
Target/Specificity Recognizes CyclinO, a 38 kDa member of the cyclin family expressed mainly during the G1 phase.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsCCNO / UNG2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCNO
Function Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking.
Cellular Location Cytoplasm. Note=Localizes to the apical part of cytoplasm
Tissue Location Present in respiratory cells (at protein level).
Volume 50 µl
Citations (0)

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Background

Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking.

References

Muller S.J.,et al.Biochim. Biophys. Acta 1088:197-207(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Muller S.J.,et al.J. Biol. Chem. 268:1310-1319(1993).

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$ 395.00
Cat# ALS14920
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