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CR2 / CD21 Antibody (clone Bu32)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IP, FC |
|---|---|
| Primary Accession | P20023 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | Bu32 |
| Calculated MW | 113kDa |
| Dilution | Flo (1:50-1:200), IHC-P (10 µg/ml), |
| Gene ID | 1380 |
|---|---|
| Other Names | Complement receptor type 2, Cr2, Complement C3d receptor, Epstein-Barr virus receptor, EBV receptor, CD21, CR2, C3DR |
| Target/Specificity | Recognizes human CD21, a 145kD cell surface glycoprotein expressed by mature B lymphocytes, follicular dendritic cells, subsets of normal thymocytes and subsets of T cells. The CD21 molecule acts as a receptor for complement components C3d, C3dg and ... |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | CR2 / CD21 Antibody (clone Bu32) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CR2 |
|---|---|
| Synonyms | C3DR |
| Function | Receptor for complement C3, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU (PubMed:7753047). Participates in B lymphocytes activation (PubMed:7753047). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.
References
Fujisaku A.,et al.J. Biol. Chem. 264:2118-2125(1989).
Weis J.J.,et al.J. Exp. Med. 167:1047-1066(1988).
Moore M.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:9194-9198(1987).
Barel M.,et al.Mol. Immunol. 35:1025-1031(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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