|Application ||IHC-P, IP, Flo|
|Dilution||Flo (1:50-1:200), IHC-P (10 µg/ml),|
|Other Names||Complement receptor type 2, Cr2, Complement C3d receptor, Epstein-Barr virus receptor, EBV receptor, CD21, CR2, C3DR|
|Target/Specificity||Recognizes human CD21, a 145kD cell surface glycoprotein expressed by mature B lymphocytes, follicular dendritic cells, subsets of normal thymocytes and subsets of T cells. The CD21 molecule acts as a receptor for complement components C3d, C3dg and ...|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||CR2 / CD21 Antibody (clone Bu32) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.
Fujisaku A.,et al.J. Biol. Chem. 264:2118-2125(1989).
Weis J.J.,et al.J. Exp. Med. 167:1047-1066(1988).
Moore M.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:9194-9198(1987).
Barel M.,et al.Mol. Immunol. 35:1025-1031(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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