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NDUFS1 Antibody (Internal)

Goat Polyclonal Antibody

     
  • WB - NDUFS1 Antibody (Internal) ALS14935
    NDUFS1 antibody (0.3 ug/ml) staining of Human Heart lysate (35 ug protein/ml in RIPA buffer).
  • IHC - NDUFS1 Antibody (Internal) ALS14935
    Anti-NDUFS1 antibody IHC of human heart.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P28331
Reactivity Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Goat, Horse, Xenopus, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 79kDa
Dilution ELISA (1:64000), IHC-P (5 µg/ml), WB (0.3-1 µg/ml)
Additional Information
Gene ID 4719
Other Names NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial, 1.6.5.3, 1.6.99.3, Complex I-75kD, CI-75kD, NDUFS1
Target/Specificity Human NDUFS1.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsNDUFS1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NDUFS1
Function Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized.
Cellular Location Mitochondrion inner membrane.
Research Areas
Citations (0)

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Background

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized.

References

Chow W.,et al.Eur. J. Biochem. 201:547-550(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.

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$ 395.00
Cat# ALS14935
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