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EPB41L4B Antibody (Internal)

Goat Polyclonal Antibody

     
  • IHC - EPB41L4B Antibody (Internal) ALS14950
    Anti-EPB41L4B antibody IHC of human adrenal.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q9H329
Reactivity Human, Rabbit, Monkey, Dog
Host Goat
Clonality Polyclonal
Calculated MW 100kDa
Dilution ELISA (1:64000), IHC-P (3.75 µg/ml),
Additional Information
Gene ID 54566
Other Names Band 4.1-like protein 4B, FERM-containing protein CG1, Protein EHM2, EPB41L4B, EHM2
Target/Specificity Human EPB41L4B. This antibody is expected to recognise both reported isoforms (NP_060894.2; NP_061987.3).
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsEPB41L4B Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EPB41L4B
Synonyms EHM2, LULU2 {ECO:0000303|PubMed:22006950
Function Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18 (By similarity). Involved in the regulation of the circumferential actomyosin belt in epithelial cells (PubMed:22006950). Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing (PubMed:23664528). May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation (PubMed:14521927).
Cellular Location Cytoplasm. Cell junction, tight junction Note=Accumulates along apical cell-cell boundaries and is also detected in the cytoplasm in a punctate manner
Tissue Location Expressed at higher levels in acute wounds than chronic wounds with increased expression in healing wounds, especially at the leading wound edge (PubMed:23664528). Isoform 1 is highly expressed in brain. Isoform 2 is highly expressed in testis with lower levels in prostate and breast (PubMed:14521927)
Research Areas
Citations (0)

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References

Chadwick B.P.,et al.Mamm. Genome 11:81-83(2000).
Shimizu K.,et al.Genomics 65:113-120(2000).
Humphray S.J.,et al.Nature 429:369-374(2004).

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$ 395.00
Cat# ALS14950
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