|Application ||WB, IHC-P, IF, ICC, IP|
|Reactivity||Human, Mouse, Rat|
|Dilution||ICC (0.1-1 µg/ml), IHC-P (10 µg/ml), IP (1-10 µg/ml), WB (1-10 µg/ml) ,|
|Other Names||Short transient receptor potential channel 7, TrpC7, Transient receptor protein 7, TRP-7, hTRP7, TRPC7, TRP7|
|Target/Specificity||Detects ~100 kD protein.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||TRPC7 Antibody (aa845-862, clone S64A-36) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Nucleus envelope|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion.
Murphy C.T.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Xu S.-Z.,et al.Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
Aptel H.,et al.Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
Schmutz J.,et al.Nature 431:268-274(2004).
Lussier M.P.,et al.J. Biol. Chem. 280:19393-19400(2005).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.