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TRPC7 Antibody (aa845-862, clone S64A-36)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, ICC, IP |
|---|---|
| Primary Accession | Q9HCX4 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | S64A-36 |
| Calculated MW | 100kDa |
| Dilution | ICC (0.1-1 µg/ml), IHC-P (10 µg/ml), IP (1-10 µg/ml), WB (1-10 µg/ml) , |
| Gene ID | 57113 |
|---|---|
| Other Names | Short transient receptor potential channel 7, TrpC7, Transient receptor protein 7, TRP-7, hTRP7, TRPC7, TRP7 |
| Target/Specificity | Detects ~100 kD protein. |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | TRPC7 Antibody (aa845-862, clone S64A-36) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRPC7 |
|---|---|
| Synonyms | TRP7 |
| Function | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G- protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Nucleus envelope |
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Provided below are standard protocols that you may find useful for product applications.
Background
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion.
References
Murphy C.T.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Xu S.-Z.,et al.Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
Aptel H.,et al.Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
Schmutz J.,et al.Nature 431:268-274(2004).
Lussier M.P.,et al.J. Biol. Chem. 280:19393-19400(2005).
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