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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   TNFSF10 / TRAIL Antibody (aa31-80)   

TNFSF10 / TRAIL Antibody (aa31-80)

Rabbit Polyclonal Antibody

     
  • IF - TNFSF10 / TRAIL Antibody (aa31-80) ALS15160
    Immunofluorescence of A549 cells, using CD253 Antibody.
  • WB - TNFSF10 / TRAIL Antibody (aa31-80) ALS15160
    Western blot of extracts from HUVEC cells/293 cells, using CD253 Antibody.
  • IHC - TNFSF10 / TRAIL Antibody (aa31-80) ALS15160
    Anti-TRAIL antibody IHC of human kidney, tubules.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P50591
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 33kDa
Dilution ELISA (1:20000), IF (1:100-1:500), IHC-P (10 µg/ml), WB (1:500-1:1000) ,
Additional Information
Gene ID 8743
Other Names Tumor necrosis factor ligand superfamily member 10, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, Protein TRAIL, CD253, TNFSF10, APO2L, TRAIL
Target/Specificity CD253 Antibody detects endogenous levels of total CD253 protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsTNFSF10 / TRAIL Antibody (aa31-80) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFSF10
Synonyms APO2L, TRAIL
Function Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Cellular Location Membrane; Single-pass type II membrane protein
Tissue Location Widespread; most predominant in spleen, lung and prostate
Research Areas
Citations (0)

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Background

Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.

References

Wiley S.R.,et al.Immunity 3:673-682(1995).
Pitti R.M.,et al.J. Biol. Chem. 271:12687-12690(1996).
Schnepple D.J.,et al.J. Biol. Chem. 286:35742-35754(2011).
Woods D.C.,et al.Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS15160
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