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CEA / Carcinoembryonic Antigen Antibody (clone 37B6)

Mouse Monoclonal Antibody

     
  • WB - CEA / Carcinoembryonic Antigen Antibody (clone 37B6) ALS15195
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, IP
Primary Accession P06731
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 37B6
Calculated MW 76796 Da
Dilution IHC-P (1:200), WB (1:250),
Additional Information
Gene ID 1048
Other Names Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen, CEA, Meconium antigen 100, CD66e, CEACAM5, CEA
Reconstitution & Storage Long term: -20°C; Short term: -20°C
PrecautionsCEA / Carcinoembryonic Antigen Antibody (clone 37B6) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CEACAM5
Synonyms CEA
Function Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050).
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane. Cell surface Note=Localized to the apical glycocalyx surface
Tissue Location Expressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
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$ 467.50
Cat# ALS15195
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