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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   CFB / Complement Factor B Antibody   

CFB / Complement Factor B Antibody

Goat Polyclonal Antibody

     
  • IHC - CFB / Complement Factor B Antibody ALS15237
    Anti-CFB / Factor B antibody IHC of human adrenal.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, ID
Primary Accession P00751
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 86kDa
Dilution IHC-P (1:200)
Additional Information
Gene ID 629
Other Names Complement factor B, 3.4.21.47, C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, Complement factor B Ba fragment, Complement factor B Bb fragment, CFB, BF, BFD
Target/Specificity Human CFB / Factor B. In immunoelectrophoresis against human EDTA plasma a single precipitin line is obtained in the beta-2 region. The antiserum does not react with any other protein component of human serum or plasma. Cross-reactivity The antiserum ...
Reconstitution & Storage Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze/thaw cycles. Store undiluted.
PrecautionsCFB / Complement Factor B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CFB
Synonyms BF, BFD
Function Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B- lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B- lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

References

Davrinche C.,et al.Immunogenetics 32:309-312(1990).
Mejia J.E.,et al.Hum. Immunol. 39:49-53(1994).
Schwaeble W.,et al.Immunobiology 188:221-232(1993).
Horiuchi T.,et al.Mol. Immunol. 30:1587-1592(1993).
Jaatinen T.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS15237
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