|Application ||WB, IHC-P, E|
|Dilution||IHC-P (1:100), WB (1:500-1:1000),|
|Other Names||60 kDa SS-A/Ro ribonucleoprotein, 60 kDa Ro protein, 60 kDa ribonucleoprotein Ro, RoRNP, Ro 60 kDa autoantigen, Sjoegren syndrome antigen A2, Sjoegren syndrome type A antigen, SS-A, TROVE domain family member 2, TROVE2, RO60, SSA2|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||TROVE2 Antibody (clone 2B4) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation.|
|Cellular Location||Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs|
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Provided below are standard protocols that you may find useful for product applications.
RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation.
Deutscher S.L.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:9479-9483(1988).
Ben-Chetrit E.,et al.J. Clin. Invest. 83:1284-1292(1989).
Buyon J.P.,et al.Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.
Han Q.,et al.Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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