EIF4A2 Antibody (aa50-100)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q14240 |
Reactivity | Human, Mouse, Monkey, Chicken, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 46kDa |
Dilution | WB (0.02-0.05 µg/ml) |
Gene ID | 1974 |
---|---|
Other Names | Eukaryotic initiation factor 4A-II, eIF-4A-II, eIF4A-II, 3.6.4.13, ATP-dependent RNA helicase eIF4A-2, EIF4A2, DDX2B, EIF4F |
Target/Specificity | Human EIF4A2 |
Reconstitution & Storage | Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C. |
Precautions | EIF4A2 Antibody (aa50-100) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | EIF4A2 |
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Synonyms | DDX2B, EIF4F |
Function | ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
References
Sudo K.,et al.Cytogenet. Cell Genet. 71:385-388(1995).
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Li W.,et al.J. Biol. Chem. 276:29111-29115(2001).
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